Niklas Heinzler

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New drugs for the treatment of multiple myeloma (MM) comprise immunomodulatory substances such as lenalidomide and related compounds. While lenalidomide has found its way into first-line treatment as well as into relapse therapy, little is known about lenalidomide effects on normal hematopoietic stem and progenitor cells (HSPCs). In this study, we(More)
OBJECTIVES The purpose of this study was to evaluate the impact of three novel iterative metal artefact (iMAR) algorithms on image quality and artefact degree in chest CT of patients with a variety of thoracic metallic implants. METHODS 27 postsurgical patients with thoracic implants who underwent clinical chest CT between March and May 2015 in clinical(More)
To evaluate the accuracy of size-specific dose estimate (SSDE) calculation from center slice with water-equivalent diameter (Dw) and effective diameter (Deff). A total of 1812 CT exams (1583 adult and 229 pediatric) were included in this retrospective study. Dw and Deff were automatically calculated for all slices of each scan. SSDEs were calculated with(More)
PURPOSE The study sought to assess the frequency and prognostic value of hyperattenuating adrenal glands on contrast-enhanced computed tomography (CT) scans of surgical intensive care unit (ICU) patients with acute clinical deterioration. METHODS Eighty-eight consecutive ICU patients (63.2 ± 14.5 years of age) were included in this retrospective analysis.(More)
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