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PURPOSE To describe the content and potentials of the new Swedish national register on prescribed and dispensed medicines. METHODS The Swedish Prescribed Drug Register contains information about age, sex and unique identifier of the patient as well as the prescriber's profession and practice. Information regarding drug utilization and expenditures for(More)
OBJECTIVES The association between coffee consumption, type 2 diabetes and impaired glucose tolerance was examined. In addition, indicators of insulin sensitivity and beta-cell function according to homeostasis model assessment were studied in relation to coffee consumption. DESIGN Population-based cross-sectional study. SETTING AND SUBJECTS The study(More)
AIMS To determine the cancer incidence in Swedish cabin crew. METHODS Cancer incidence of cabin crew at the Swedish Scandinavian Airline System (SAS) (2324 women and 632 men) employed from 1957 to 1994 was determined during 1961-96 from the Swedish National Cancer Register. The cancer incidence in cabin crew was compared with that of the general Swedish(More)
Sirs—A possible protective effect of coffee consumption on the risk of developing type 2 diabetes was suggested recently in a study by van Dam and Feskens. 1 This finding is supported by a Japanese study, 2 whereas no protective effect of coffee was reported in a recent Finnish study 3 and in Pima Indians. 4 This issue is important to study further,(More)
OBJECTIVE The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. Information on alcohol, smoking, diet,(More)
Epidemiological evidence indicates that individuals with type 2 diabetes are at an increased risk of cancer. Elevated glucose levels, below the diagnostic threshold for diabetes, have also been suggested to be associated with increased cancer risks. We investigated possible associations between glucose levels and the risk of breast, endometrial, and ovarian(More)
AIMS Women, particularly younger women, hospitalized with acute myocardial infarction have been found to have poorer prognosis than men. A large proportion of deaths due to myocardial infarction, however, occur in the pre-hospital phase. We set out to analyse age-specific sex differences in survival after myocardial infarction at different time intervals(More)
Finnish men have higher coronary heart disease (CHD) mortality than Swedish men do. To assess the impact of migration to a country with lower CHD mortality on subclinical atherosclerosis, we measured early functional and structural atherosclerotic vascular changes in twins discordant for migration from Finland to Sweden. Conventional CHD risk factors,(More)
BACKGROUND Obesity is a risk factor for breast and ovarian cancer; the mechanisms of action are not completely understood. Perturbed lipid metabolism often accompanies obesity; we therefore ascertained the associations between lipid components and breast and ovarian cancer risk in a prospective cohort study. METHODS A total of 234,494 women with baseline(More)
Cosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime doses did not exceed 80 mSv. All-cause(More)