Nighat Noureen

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Histone deacetylase inhibitors (HDACIs) have emerged as efficient chemotherapeutic agents. Molecular docking studies of hydroxamtes, biphenyl and benzamide derivatives using Human HDAC8 with pdb id: 1T69 have been carried out in order to find the most active anticancer HDACI. AutoDock 4.0 has been used for docking. The most active lead compound has been(More)
Analysis of gene expression data includes classification of the data into groups and subgroups based on similar expression patterns. Standard clustering methods for the analysis of gene expression data only identifies the global models while missing the local expression patterns. In order to identify the missed patterns biclustering approach has been(More)
The enteropathogen Campylobacter jejuni is a global health disaster, being one of the leading causes of bacterial gastroenteritis. Here, we present the draft genome sequence of C. jejuni strain cj255, isolated from a chicken source in Islamabad, Pakistan. The draft genome sequence will aid in epidemiological studies and quarantine of this broad-host-range(More)
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