Nigel G. Anderson

Learn More
Two-dimensional (2-D) cranial ultrasound (US) is the principal method for the detection of cerebral injury in the newborn. The aim of this study was to compare 2-D sonographic methods with more advanced 3-D magnetic resonance imaging (MRI) for assessing brain structure. From July 1998 to November 2000, we conducted a prospective methodological study(More)
OBJECTIVE There is an urgent need for a bedside method to assess the effectiveness of neonatal therapies designed to improve cerebral development in very low birth-weight infants. The aim of this study was to assess the impact of preterm birth on the serial growth of the corpus callosum and how soon it could be detected after birth with cranial ultrasound.(More)
BACKGROUND AND PURPOSE It is desirable to develop a bedside method for assessing cerebral development in the very premature infant to monitor the effectiveness of interventions aimed at improving cerebral development. Our aim was to describe the growth trajectory of the corpus callosum (CC) on cranial sonography in very premature infants. METHODS We(More)
The energy spectrum of X-ray photons after passage through an absorber contains information about its elemental composition. Thus, tissue characterisation becomes feasible provided that absorption characteristics can be measured or differentiated. Dual-energy CT uses two X-ray spectra enabling material differentiation by analysing material-dependent(More)
BACKGROUND Clinical assessment of gestational age for very-low-birth-weight infants is often inaccurate. Survival rates are more dependent on gestational age than on the birth weight. OBJECTIVE To assess whether cerebellar vermis diameter might predict gestational age in infants under 2,000 g and/or under 32 weeks' gestation. MATERIALS AND METHODS We(More)
OBJECTIVE The purpose of this study was to correlate normal brain anatomy as seen on posterior fontanelle cranial sonography with anatomical sections of the premature infant brain. MATERIALS AND METHODS Images obtained from 93 cranial ultrasound examinations performed via both the anterior and posterior fontanelle in 53 infants, ranging in gestational age(More)
The energy information acquired using spectral X-ray detectors allows noninvasive identification and characterization of chemical components of a material. To achieve this, it is important that the energy response of the detector is calibrated. The established techniques for energy calibration are not practical for routine use in pre-clinical or clinical(More)
Prognosis of the very low birth weight infant depends more on gestational age than birth weight, but clinical assessment of gestational age of very low birth weight infants is inaccurate. We wished to determine how well cerebellar vermis dimensions might predict gestational age in infants of birth weight less than 2000 g. We obtained suitable midline(More)
Progesterone, 20alpha-dihydroprogesterone, estrone and estradiol-17beta concentrations were estimated by radioimmunoassay in blood plasma from uterine, uteroovarian and femoral veins of rhesus monkeys (Macaca mulatta) on days 22, 49, 128 and 160 of gestation. Steroids were consistently more concentrated in uterine and uteroovarian that in femoral venous(More)