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  • Thomas Lindenstrøm, Niels Peter Hell Knudsen, Else Marie Agger, Peter Andersen
  • Medicine, Biology
  • The Journal of Immunology
  • 2013 (First Publication: 15 June 2013)
  • The bacille Calmette–Guérin vaccine provides very efficient protection in standard animal models of Mycobacterium tuberculosis challenge. We show in this article that although bacille Calmette–GuérinExpand
  • Niels Peter Hell Knudsen, Anja Olsen, +14 authors Else Marie Agger
  • Medicine, Biology
  • Scientific reports
  • 2016 (First Publication: 21 January 2016)
  • The majority of vaccine candidates in clinical development are highly purified proteins and peptides relying on adjuvants to enhance and/or direct immune responses. Despite the acknowledged need forExpand
  • Niels Peter Hell Knudsen, Sara Nørskov-Lauritsen, +5 authors Claus Aagaard
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2014 (First Publication: 6 January 2014)
  • Significance Despite the availability of a number of antibiotics and extensive use of the live vaccine bacillus Calmette–Guérin, tuberculosis remains a major global health problem. Antigen 85 is byExpand
  • Helena Strand Clemmensen, Niels Peter Hell Knudsen, +7 authors Claus Aagaard
  • Medicine
  • Scientific reports
  • 2017 (First Publication: 24 April 2017)
  • Although Mycobacterium tuberculosis (M.tb) DK9897 is an attenuated strain, it was isolated from a patient with extrapulmonary tuberculosis and vaccination with a subunit vaccine (H56) induced poorExpand