Learn More
INTRODUCTION The aim of the study was to assess the influence of annual volume and factors related to intensive care unit (ICU) organization on in-hospital mortality among patients admitted to the ICU with severe sepsis. METHODS A retrospective cohort study was conducted using the database of the Dutch National Intensive Care Evaluation (NICE) registry.(More)
OBJECTIVE To investigate the behavior of predictive performance measures that are commonly used in external validation of prognostic models for outcome at intensive care units (ICUs). STUDY DESIGN AND SETTING Four prognostic models (Simplified Acute Physiology Score II, the Acute Physiology and Chronic Health Evaluation II, and the Mortality Probability(More)
AIMS To assess the effects of multi-disciplinary cardiac rehabilitation (CR) on survival in the full population of patients with an acute coronary syndrome (ACS) and patients that underwent coronary revascularization and/or heart valve surgery. METHODS AND RESULTS Population-based cohort study in the Netherlands using insurance claims database covering(More)
Sensitivity analysis is a method to investigate the effects of varying a model's parameters on its predictions. It was recently suggested as a suitable means to facilitate quantifying the joint probability distribution of a Bayesian belief network. This article presents practical experience with performing sensitivity analyses on a belief network in the(More)
Clinical decision support systems (CDSSs) differ from other health information systems in their aim to directly influence the decision-making behaviour of healthcare professionals. As a result, CDSSs face additional challenges with respect to user acceptance. The objective of this study was to investigate subjective usability of a guideline-based CDSS for(More)
PURPOSE Clinical practice guidelines often contain ambiguities, inconsistencies, and logical errors that hamper implementation of these guidelines in practice. As guideline formalization is useful to verify the logical structure, consistency, and completeness of guidelines, several authors have argued that the formalization of guidelines concurrent with(More)
OBJECTIVE To evaluate patients' preferences for message features and assess their relationships with health literacy, monitor-blunter coping style, and other patient-dependent characteristics. METHODS Patients with coronary heart disease completed an internet-based survey, which assessed health literacy and monitor-blunter coping style, as well as various(More)
OBJECTIVE To determine the extent to which computerised decision support can improve concordance of multidisciplinary teams with therapeutic decisions recommended by guidelines. DESIGN Multicentre cluster randomised trial. PARTICIPANTS Multidisciplinary cardiac rehabilitation teams in Dutch centres and their cardiac rehabilitation patients. (More)
OBJECTIVE To determine whether teledermatologic consultations can reduce referrals to a dermatologist by general practitioners (GPs). DESIGN Multicenter cluster randomized controlled trial. SETTING AND PARTICIPANTS We recruited 85 GPs from 35 general practices in 2 regions in the Netherlands (Almere and Zeist); 5 dermatologists from 2 nonacademic(More)