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Clinical decision support systems (CDSSs) differ from other health information systems in their aim to directly influence the decision-making behaviour of healthcare professionals. As a result, CDSSs face additional challenges with respect to user acceptance. The objective of this study was to investigate subjective usability of a guideline-based CDSS for(More)
OBJECTIVE To determine the extent to which computerised decision support can improve concordance of multidisciplinary teams with therapeutic decisions recommended by guidelines. DESIGN Multicentre cluster randomised trial. PARTICIPANTS Multidisciplinary cardiac rehabilitation teams in Dutch centres and their cardiac rehabilitation patients. (More)
OBJECTIVE To study posttraumatic stress disorder (PTSD) in parents after unexpected pediatric intensive care unit (PICU) treatment of their child and to identify risk factors for its development. METHOD Parents completed PTSD questionnaires 3 and 9 months (N = 190) after PICU treatment. Risk factors included pretrauma data, medical data, social(More)
OBJECTIVE To introduce the focus theme of Methods of Information in Medicine on Intelligent Data Analysis for Knowledge Discovery, Patient Monitoring and Quality Assessment. METHODS Based on two workshops on Intelligent Data Analysis in bioMedicine (IDAMAP) held in Washington, DC, USA (2010) and Bled, Slovenia (2011), six authors were invited to write(More)
INTRODUCTION The aim of the study was to assess the influence of annual volume and factors related to intensive care unit (ICU) organization on in-hospital mortality among patients admitted to the ICU with severe sepsis. METHODS A retrospective cohort study was conducted using the database of the Dutch National Intensive Care Evaluation (NICE) registry.(More)
AIMS To assess the effects of multi-disciplinary cardiac rehabilitation (CR) on survival in the full population of patients with an acute coronary syndrome (ACS) and patients that underwent coronary revascularization and/or heart valve surgery. METHODS AND RESULTS Population-based cohort study in the Netherlands using insurance claims database covering(More)
BACKGROUND Requirements development is a crucial part of eHealth design. It entails all the activities devoted to requirements identification, the communication of requirements to other developers, and their evaluation. Currently, a requirements development approach geared towards the specifics of the eHealth domain is lacking. This is likely to result in a(More)
Sensitivity analysis is a method to investigate the effects of varying a model's parameters on its predictions. It was recently suggested as a suitable means to facilitate quantifying the joint probability distribution of a Bayesian belief network. This article presents practical experience with performing sensitivity analyses on a belief network in the(More)
PURPOSE Clinical practice guidelines often contain ambiguities, inconsistencies, and logical errors that hamper implementation of these guidelines in practice. As guideline formalization is useful to verify the logical structure, consistency, and completeness of guidelines, several authors have argued that the formalization of guidelines concurrent with(More)