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Inhibition of P. falciparum PFATP6 by curcumin and its derivatives: a bioinformatic study.
Curcumin, a yellow spice has been shown to have many pathological uses including cancer and malaria. Recent experimental data have shown the inhibitory effect of curcumin and its two derivatives onExpand
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Important amino acid residues of hexachlorocyclohexane dehydrochlorinases (LinA) for enantioselective transformation of hexachlorocyclohexane isomers
LinA-type1 and LinA-type2 are two well-characterized variants of the enzyme ‘hexachlorocyclohexane (HCH)-dehydrochlorinase’. They differ from each other at ten amino acid positions and exhibitExpand
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Synergistic approaches unraveling regulation and aggregation of intrinsically disordered β-amyloids implicated in Alzheimer's disease.
Alzheimer's disease is a severe brain illness that causes vast numbers of nerve cells in the brain to die, driven by the production and deposition of amyloid beta (Aβ) peptides. IntrinsicallyExpand
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Tinospora cordifolia (Giloy) is one of the most important medicinal plant and the forms an important drug of the Ayurvedic system of Medicine. It is prescribed for many diseases such as generalExpand
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Novel LinA Type 3 δ-Hexachlorocyclohexane Dehydrochlorinase
ABSTRACT LinA is the first enzyme of the microbial degradation pathway of a chlorinated insecticide, hexachlorocyclohexane (HCH), and mediates the dehydrochlorination of α-, γ-, and δ-HCH. Its twoExpand
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Specific Keratinase Derived Designer Peptides Potently Inhibit A β Aggregation Resulting in Reduced Neuronal Toxicity and Apoptosis.
Compelling evidences implicate self-assembly of amyloid- β (A β 1-42) peptides into soluble oligomers and fibrils as a major underlying event in Alzheimer's disease (AD) pathogenesis. Herein, weExpand
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Wolbachia: A prospective solution to mosquito borne diseases
Malaria, Dengue, Japanese encephalitis Chikungunya, lymphatic filariasis etc. are among the common vector borne diseases distributed across the world. Mosquitoes are main cause of transmission ofExpand
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Wing patterning in faster developing Drosophila is associated with high ecdysone titer and wingless expression
'Developmental robustness' is the ability of biological systems to maintain a stable phenotype despite genetic, environmental or physiological perturbations. In holometabolous insects, accurateExpand
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A Review and Meta-Analysis for Efficient Intrusion Detection on KDD Dataset
In any network based system and organization identifying the possible attacks is very crucial and important to perceive the data integrity and security. Expand
Outbreak of Aspergillus fumigatus in an organized Emu farm in Indore, India.
Detailed postmortem examination was conducted on eleven emu chicks presented to the Department of Veterinary Pathology, College of Veterinary and Animal Science, Mhow, MP, India from local emu farmExpand
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