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Expression of the growth-promoting integrin alphavbeta6 in colon cancer cells induces gelatinase B secretion and activation, the inhibition of which abolishes alphavbeta6-mediated tumour cell growth within a collagen matrix. Herein, we show that high cell density selectively enhances alphavbeta6 expression in a protein kinase C (PKC)-dependent manner in(More)
OBJECTIVE To determine whether ultrasound-guided core needle biopsy is a safe and reliable investigation in cases of parotid swelling in which fine needle aspiration cytology has failed to give a definitive diagnosis. DESIGN Analysis of 66 ultrasound-guided core biopsy specimens of the parotid gland (the largest series reported thus far) sample number(More)
The aim of this study was to assess nurses' performance related to control and prevention of nosocomial respiratory infection in artificially ventilated patients and to estimate incidence and the causative microorganisms of such infection. The study was conducted on 30 ventilated patients and 30 nurses who were responsible for their care. An observation(More)
Triple-negative breast cancer (TNBC) represents an aggressive cancer subtype characterized by the lack of expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). The independence of TNBC from these growth promoting factors eliminates the efficacy of therapies which specifically target them, and(More)
A 59-year-old man with critical claudication underwent left femoro-anterior bypass grafting, which was uneventful. The graft was tunneled medially across the knee, then anterior to the tibia. His symptoms recurred 1 year later and he was found to have critical stenosis of the vein graft just proximal to the anterior tibial arterial anastomosis. This was(More)
We investigated the potential of symplocomoside (1) and symponoside (2), glycosides isolated from the bark of Symplocos racemosa to inhibit thymidine phosphorylase (TP) activity and associated angiogenesis. Compound 1 was a reversible, noncompetitive inhibitor of deoxythymidine binding to TP (IC(50) = 65.45 +/- 5.08 microM; K(i) = 62.83 +/- 2.10 microM) and(More)
BACKGROUND AND OBJECTIVES Laparoscopic adjustable gastric banding is an effective and popular bariatric surgery for weight loss in obese patients that traditionally involves up to 5 incisions. Recently, a more minimally invasive single-incision technique has been developed. In this retrospective study, we compare conventional and single-incision(More)
A Voltage Regulator which can drive on very small differential voltage is projected called Low Drop-Out Voltage Regulator (LDO). It consist of Trans-Conductance Amplifier as an Error Amplifier (EA) in accordance with it a current buffer compensation scheme. This Error Amplifier (EA) provides boost in the gain, enhanced the closed-loop bandwidth of the Low(More)
This study aimed at the assessment of the nurses' knowledge and attitudes towards epilepsy. A sample consisting of 273 nurses working in different hospital departments, at three University hospitals in Tanta, Menoufiya and Zagazig was chosen. The results revealed a deficiency in the nurses' knowledge about epilepsy. However, they had a moderately positive(More)