Nicoleta Filimon

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Structural bioinformatics approaches applied to the alpha- and beta-glycosidases from the GH4 enzyme family reveal that, despite low sequence identity, these enzymes possess quite similar global structural characteristics reflecting a common reaction mechanism. Locally, there are a few distinctive structural characteristics of GH4 alpha- and(More)
The alcohol, consumed in great quantities and for a long period of time determines, directly or by its metabolites, serious alterations of the hepatic function and structure. The causal mechanisms underlying this disease are not fully understood. Histological features of chronic alcoholic hepatitis include: hepatocellular injury, inflammation and repair of(More)
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