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To study the regulation of herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) expression and processing in the absence of other cis and trans viral functions, a transgenic mouse containing the region encompassing the LAT promoter (LAP1) and the LAT 5' exon through the 2.0-kb intron was created. LAT expression was detectable by reverse(More)
When the sequence of the Euglena gracilis chloroplast genome was reported in 1993 the alpha-subunit gene (rpoA) of RNA polymerase appeared to be missing, based on a comparison of all putative reading frames to the then known rpoA loci. Since there has been a large increase in known rpoA sequences, the question of a Euglena chloroplast rpoA gene was(More)
3 ACKNOWLEDGMENTS First and foremost, I thank my parents and family for encouraging me to follow whatever career path I chose. I wouldn't be where I am today without their support and love, and I will always be grateful. I thank my undergraduate mentor, Richard Hallick, for giving me the chance to get my start in a lab. In addition, I thank his(More)
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