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BACKGROUND AND AIMS There is some evidence that posttraumatic stress disorder (PTSD) and early life adversity may influence metabolic outcomes such as obesity, diabetes, and cardiovascular disease. However, whether and how these interact is not clear. METHODS We analyzed data from a cross-sectional and longitudinal study to determine how PTSD severity(More)
A study of 157 psoriatic patients showed that 48.4% were HL-A 17 positive (control 6.0%). The relative risk of psoriasis in HL-A 17 positive individuals (14.7) was significantly higher than that reported from other centes, whilst that for HL-A 13 was lower. HL-A 17 was commoner in femal patients and associated with an earlier age of onset of psoriasis than(More)
OBJECTIVE This study examined whether a novel indicator of overall childhood adversity, incorporating number of adversities, severity, and chronicity, predicted central obesity beyond contributions of "modifiable" risk factors including psychosocial characteristics and health behaviors in a diverse sample of midlife adults. The study also examined whether(More)
CONTEXT Early-life adversity, defined as physical, emotional, or sexual abuse and neglect before 18 years of age, is associated with metabolic syndrome, obesity, and type 2 diabetes mellitus in adult life. However, the underlying mechanism is not fully understood, and whether adipomyokines are associated with early-life adversity independent of other(More)
UNLABELLED This study compared changes in speech clarity as a function of speaking context. It is well documented that words produced in sentence contexts yield higher intelligibility than words in isolation for speakers with mild to moderate dysarthria. To tease apart the effect of speaker and listener variables, the current study aimed to quantify(More)
Childhood adversity is a risk factor for adult health outcomes, including obesity and hypertension. This study examines whether childhood adversity predicted mean arterial pressure through mechanisms of central obesity and leptin, adiponectin, and/or insulin resistance, and including dietary quality. 210 Black/African Americans and White/European Americans,(More)
OBJECTIVE Adult attachment discourse patterns and current family relationship quality were examined as correlates of health behaviors and number of metabolic syndrome (MetS) criteria met, and as mediators of the link between childhood adversity and these health outcomes. METHODS A sample of 215 white/European American and black/African American adults(More)
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