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Similarities have been observed in the localization of the final position of moving visual and moving auditory stimuli: Perceived endpoints that are judged to be farther in the direction of motion in both modalities likely reflect extrapolation of the trajectory, mediated by predictive mechanisms at higher cognitive levels. However, actual comparisons of(More)
The present study reports the hemispheric specificity of spatial auditory processing in 15 healthy subjects by measuring location mismatch negativity (MMN) under free field stimulation. The aim was to decide between the partly inconsistent hypotheses of contralateral and/or right-hemispheric dominance in spatial processing in the auditory cortex. The(More)
From behavioral studies it is known that auditory spatial resolution of azimuthal space declines over age. To date, it is not clear how age affects the respective sensory auditory processing at the pre-attentive level. Here we tested the hypothesis that pre-attentive processing of behaviorally perceptible spatial changes is preserved in older adults. An(More)
The encoding of auditory spatial acuity (measured as the precision to distinguish between two spatially distinct stimuli) by neural circuits in both auditory cortices is a matter of ongoing research. Here, the event-related potential (ERP) mismatch negativity (MMN), a sensitive indicator of preattentive auditory change detection, was used to tap into the(More)
Difference in the processing of motion and static sounds in the human cortex was studied by electroencephalography with subjects performing an active discrimination task. Sound bursts were presented in the acoustic free-field between 47° to the left and 47° to the right under three different stimulus conditions: (i) static, (ii) leftward motion, and (iii)(More)
Auditory spatial processing is an important ability in everyday life and allows the processing of omnidirectional information. In this review, we report and compare data from psychoacoustic and electrophysiological experiments on sound localisation accuracy and auditory spatial discrimination in infants, children, and young and older adults. The ability to(More)
DEK is an abundant chromatin protein in metazoans reaching copy numbers of several millions/nucleus. Previous work has shown that human DEK, a protein of 375 amino acids, has two functional DNA-binding domains, of which one resides in a central part of the molecule and contains sequences corresponding to the scaffold attachment factor-box (SAF-box) domain(More)
The availability of reliable land cover information is crucial for a wide range of applications, like for example monitoring of land-use change and land degradation as well as administrative matters. In global scale, the mapping of land cover and land cover change is crucial for a reliable understanding of global processes and changes. But also on local to(More)
In vitro, the infection of human B-cells with the lymphotropic gammaherpesvirus Epstein-Barr virus (EBV) induces formation of permanently growing lymphoblastoid cell lines (LCL). In a spontaneously outgrown LCL (cell line CSIII), we detected nucleotide sequence variations of the EBV nuclear antigen 1 (EBNA1) RNA that was different from the reference(More)
Acknowledgements First of all I would like to thank Prof. Herrmann Kaufmann and Dr. Sabine Chabrillat for the opportunity to work on this project and being my supervisors from the very beginning. I am especially grateful to Sabine for keeping work not related to the project off my desk and giving me the freedom to focus on the research. Her guidance in the(More)