Nicole R. Wells

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The cannabinoid CB1 receptor antagonist/inverse agonist rimonabant (SR 141716) has been shown to block reinforcing and rewarding effects of nicotine. Research has not investigated whether the cannabinoid system is involved in the interoceptive stimulus effects of nicotine functioning as a conditional stimulus (CS). We examined the effects of rimonabant and(More)
Environmental stimuli that co-occur with tobacco use come to evoke drug-related conditioned responses (CRs) that appear involved in continued use of nicotine-containing products. In rats, nicotine can serve as a conditional stimulus (CS) for non-drug unconditioned stimuli (USs), prompting the question of whether the nicotine CS can compete with, or(More)
Exposure of coho salmon for 25 days to dilutions of sewage treatment plant effluent with river water containing added Cu (either 35 or 70 micrograms total Cu 1(-1) and an array of Cu2+ concentrations resulted in accumulations of Cu in gill and liver tissues that (a) correlated positively with the Cu2+ contents of the solutions; (b) reached a plateau(More)
Using a probability sample from a 2001 Youth Risk Behavior Survey of Asian-Pacific Islander youths in Guam, this brief study examined the outcomes for methamphetamine use on aggression and risky sexual activities. The results of the study indicated that both male and female adolescents who used methamphetamine were significantly more likely to participate(More)
Nicotine functions as a negative feature in a Pavlovian discriminated goal-tracking task. Whether withholding of responding to the conditional stimulus (CS) reflects nicotine functioning as a conditioned inhibitor is unknown. Accordingly, the present research sought to determine whether nicotine trained as a negative feature passed the(More)
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