Nicole R. Stephens

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BMI-1 and EZH2 are polycomb group (PcG) proteins that maintain self-renewal of stem cells, and are overexpressed in leukemia. To investigate the potential of PcG proteins as leukemia-associated antigens, and as targets for graft-versus-leukemia (GVL) effects, we studied cells obtained from 86 patients with chronic myeloid leukemia (CML) and 25 human(More)
A data collection program was established using GMRI staff and NOAA observers to monitor and document the bycatch of regulated groundfish and non-regulated species during the 2008-2009 shrimp season. GMRI staff sampled the catch from 137 hauls (tows) over a period of 39 days (fishing trips). Initially four boats were used to collect data, one operating in(More)
Background—T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3 + CD8 + lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patients as first therapy, but the activity of an anti-CD52(More)
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