Nicole M Mueske

Learn More
Diminished bone density and skeletal fractures are common morbidities during and following therapy for acute lymphoblastic leukemia (ALL). While cumulative doses of osteotoxic chemotherapy for ALL have been reported to adversely impact bone density, the timing of onset of this effect as well as other changes to bone structure is not well characterized. We(More)
Minimum foot clearance (MFC) as it relates to trips and falls has been extensively studied across many locomotor tasks, but examination of this body of research yields several studies with conflicting results and a wide range of MFCs within tasks. While there are several factors that may affect the MFC variability across studies (populations studied,(More)
STUDY DESIGN Retrospective Cohort INTRODUCTION Important outcomes of polliciation to treat thumb hypoplasia/aplasia include strength, function, dexterity, and quality of life. PURPOSE OF THE STUDY To evaluate outcomes and examine predictors of outcome after early childhood pollicization. METHODS 8 children (10 hands) were evaluated 3-15 years after(More)
Obesity as defined by body mass index percentile (BMI%) is strongly associated with relapse and poorer survival in childhood ALL. Whether BMI% accurately reflects body fat percentage (BF%) in this population is unknown. We conducted a prospective study assessing body composition during frontline ALL therapy. Dual-energy X-ray absorptiometry measured BF% and(More)
Dual-energy X-ray absorptiometry (DXA) of the lateral distal femur (LDF) has been suggested for patients with metal implants or joint contractures preventing DXA scanning at conventional anatomical sites. This study assessed variability in LDF DXA measures due to repeat scanning using data from 5 healthy young adults who had 3 unilateral scans with(More)
PURPOSE To compare dynamic ankle-foot orthoses (DAFOs) and adjustable dynamic response (ADR) ankle-foot orthoses (AFOs) in children with cerebral palsy. METHODS A total of 10 children with cerebral palsy (4-12 years; 6 at Gross Motor Function Classification System level I, 4 at Gross Motor Function Classification System level III) and crouch and/or(More)
Dexterity after finger pollicization (reconstruction to thumb) is critical to functional outcomes. While most tests of hand function evaluate a combination of strength, coordination, and motor control, the Strength-Dexterity (S-D) paradigm focuses on the dynamic control of fingertip forces. We evaluated 10 pollicized and 5 non-pollicized hands from 8(More)
Abnormal tibial torsion is a common pediatric problem, and there are many existing measurement methods. The purpose of this study was to compare three methods of measuring tibial torsion for its evaluation: computed tomography, physical examination, and motion capture. Twenty healthy children and 20 children with myelomeningocele underwent measures of(More)
This open-access article is published and distributed under the Creative Commons Attribution NonCommercial No Derivatives License (, which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter,(More)
BACKGROUND The pediatric spina bifida population suffers from decreased mobility and recurrent fractures. This study aimed to develop a method for quantifying bone mass along the entire tibia in youth with spina bifida. This will provide information about all potential sites of bone deficiencies. METHODS Computed tomography images of the tibia for 257(More)