Nicole Leahy

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Among mammals, genetic recombination occurs at highly delimited sites known as recombination hotspots. They are typically 1-2 kb long and vary as much as a 1,000-fold or more in recombination activity. Although much is known about the molecular details of the recombination process itself, the factors determining the location and relative activity of(More)
The success of high resolution genetic mapping of disease predisposition and quantitative trait loci in humans and experimental animals depends on the positions of key crossover events around the gene of interest. In mammals, the majority of recombination occurs at highly delimited 1-2 kb long sites known as recombination hotspots, whose locations and(More)
The US government has mandated that, in a catastrophic event, metropolitan areas need to be capable of caring for 50 burn-injured patients per million population. In New York City, this corresponds to 400 patients. There are currently 140 burn beds in the region which can be surged up to 210. To care for additional patients, hospitals without burn centers(More)
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