Nicolas Thoma

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  • Alex Pines, Mischa G. Vrouwe, Jurgen A. Marteijn, Dimitris Typas, Martijn S. Luijsterburg, Medine Cansoy +9 others
  • 2012
The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent removal of ultraviolet (UV)-induced DNA lesions by nucleotide excision repair (NER). However, how DDB2 promotes NER in chromatin is poorly understood. Here, we identify poly(ADP-ribose) polymerase 1 (PARP1) as a novel DDB2-associated factor. We demonstrate that DDB2(More)
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