The use of interactive screen media is widespread and for some users leads to pathological symptoms that are phenomenologically similar to signs of addictive disorders. Addictive use of computer games and other Internet applications, such as social media can be distinguished. In the past standard criteria to classify this new disorder were lacking. In… (More)
It is unclear whether gene regulatory changes that drive evolution at the population and species levels [1-3] can be extrapolated to higher taxonomic levels. Here, we investigated the role of cis-regulatory changes in fruit evolution within the Brassicaceae family. REPLUMLESS (RPL, At5g02030) controls development of the replum, a structure with an important… (More)
Patterning in plants requires defining boundary domains that separate and organize the development of the neighboring organs. Two papers now show how the interplay between brassinosteroid phytohormones and frontier genes contributes to boundary formation in plants.
UNLABELLED BACKGROUND Mid to late adolescence is characterised by a vulnerability to problematic substance use since the consumption of alcohol and illicit drugs is frequently initiated and increased in this life period. While the detrimental long- and short-term effects of problematic consumption patterns in adolescence pose a major public health… (More)
Carpels are leaf-like structures that bear ovules, and thus play a crucial role in the plant life cycle. In angiosperms, carpels are the last organs produced by the floral meristem and they differentiate a specialized meristematic tissue from which ovules develop. Members of the three-amino-acid-loop-extension (TALE) class of homeoproteins constitute major… (More)
Charged particle identification (PID) is a key input for the physics program of the SuperB experiment. In the barrel region, the main detector for K/π separation will be the 'Focusing Detector of Internally Reflected Cherenkov light' (FDIRC), the successor of the successful BABAR DIRC, which camera has been completely redesigned. In addition, R&D is ongoing… (More)
Variability is defined as the ability of a software artefact to be changed or customised to be used in multiple contexts. This paper outlines variability issues through reusable component development, and in particular, in Business Component (BC) development. The main ideas of this work are (a) to address variability issues through BC development, (b) to… (More)