Nicola van der Walt

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A possible route for the production of no-carrier-added (n.c.a.) 73Se (T(1/2) = 7.1 h) and 75Se (120 d) is introduced. D,L-2-Amino-4-([73Se]methyl-seleno) butanoic acid (D,L-[73Se]selenomethionine) with an overall radiochemical yield of > 40% could be prepared via a 3-step polymer-supported synthesis after successful separation of 73Se from KBr targets.(More)
Gestational diabetes mellitus (GDM) is a common obstetric complication. Half of women who have GDM will go on to develop type 2 diabetes. Understanding the mechanisms by which this occurs requires an animal model of GDM without ongoing diabetes at conception. C57Bl/6J mice react acutely to a high-fat, high-sucrose (HFHS) challenge. Here, we hypothesized(More)
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