Nicola Pietro Montaldo

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SB056 is a novel semi-synthetic antimicrobial peptide with a dimeric dendrimer scaffold. Active against both Gram-negative and -positive bacteria, its mechanism has been attributed to a disruption of bacterial membranes. The branched peptide was shown to assume a β-stranded conformation in a lipidic environment. Here, we report on a rational modification of(More)
Antimicrobial peptides (AMPs) are effectors of the innate immunity of most organisms. Their role in the defense against pathogen attack and their high selectivity for bacterial cells make them attractive for the development of a new class of antimicrobial drugs. The N-terminal fragment of the frog-skin peptide esculentin-1b (Esc(1-18)) has shown(More)
Recent developments have made land-surface models (LSMs) more complex through the inclusion of more processes and controlling variables, increasing numbers of parameters and uncertainty in their estimates. To overcome these uncertainties, prior to applying a distributed LSM over the whole Toce basin (Italian Alps), a field campaign was carried out at an(More)
Discussions This discussion paper is/has been under review for the journal Hydrology and Earth System Sciences (HESS). Please refer to the corresponding final paper in HESS if available. Abstract There is increased interest in the interplay between vegetation conditions and overland flow generation. The literature is unclear on this relationship and there(More)
Papers published in Hydrology and Earth System Sciences Discussions are under open-access review for the journal Hydrology and Earth System Sciences Abstract Mediterranean ecosystems are commonly heterogeneous savanna-like ecosystems, with contrasting plant functional types (PFTs, e.g., grass and woody vegetation) competing for the water use. Mediterranean(More)
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