Nicola L. Stevenson

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Collagen is the most abundant protein in the animal kingdom. It is of fundamental importance during development for cell differentiation and tissue morphogenesis as well as in pathological processes such as fibrosis and cancer cell migration. However, our understanding of the mechanisms of procollagen secretion remains limited. Here, we show that TFG(More)
The C-terminal anchored golgin giantin (golgb1) plays a crucial role in Golgi structure and acts as a tether for COPI vesicles at the cis-and-medial Golgi. Recently, our lab has shown that in addition to its known roles in membrane trafficking, giantin is required for ciliogenesis in vitro. A functional knockout of giantin exists. The osteochondrodysplasia(More)
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