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  • Haytham Dahlawi, Nicola Jordan-Mahy, Malcolm R Clench, Gordon J McDougall, Christine Lyn Maitre
  • Chemistry, Medicine
  • Food science & nutrition
  • 2013 (First Published: 1 March 2013)
  • Pomegranates have shown great promise as anti-cancer agents in a number of cancers including clinical trials in prostate cancer. We have previously shown pomegranate juice (PGJ) induced apoptosis andContinue Reading
  • Amani A. Mahbub, Christine L. Le Maitre, Sarah Haywood-Small, Neil A Cross, Nicola Jordan-Mahy
  • Biology, Medicine
  • Cell Death and Disease
  • 2015 (First Published: 1 December 2015)
  • Recently published in Nature: Cell Death and Discovery, Mahbub et al.1 have demonstrated that polyphenols can synergistically enhance the action of the topoisomerase II inhibitors: doxorubicin andContinue Reading
  • Rasha Hatem Saeed Dosh, AhmedA Essa, Nicola Jordan-Mahy, Christopher Sammon, Christine L Le Maitre
  • Materials Science, Medicine
  • Acta biomaterialia
  • 2017 (First Published: 1 October 2017)
  • The human intestinal cell lines: Caco-2 and HT29-MTX cells have been used extensively in 2D and 3D cell cultures as simple models of the small intestinal epithelium in vitro. This study aimed toContinue Reading
  • Amani A. Mahbub, Christine L Le Maitre, Sarah Haywood-Small, Gordon J McDougall, Neil A Cross, Nicola Jordan-Mahy
  • Biology, Medicine
  • Anti-cancer agents in medicinal chemistry
  • 2013 (First Published: 31 December 2013)
  • BACKGROUND Mortality rates for leukemia are high despite considerable improvements in treatment. Since polyphenols exert pro-apoptotic effects in solid tumors, our study investigated the effects ofContinue Reading