Nicola Funel

Learn More
Highly invasive tumor cells are characterized by a metabolic switch, known as the Warburg effect, from "normal" oxidative phosphorylation to increased glycolysis even under sufficiently oxygenated conditions. This dependence on glycolysis also confers a growth advantage to cells present in hypoxic regions of the tumor. One of the key enzymes involved in(More)
MSCs transplantation and imaging by using magnetic multiwall carbon nanotubes O. Vittorio, P. Parchi, N. Funel, M. Masini, A. Cuschieri, M. Cecchini, M. Lisanti Istituto Nanoscienze-CNR and Scuola Normale Superiore, Nest Lab, Pisa, Italy University of Pisa, Orthopedic Deptartment, Pisa, Italy University of Pisa, Department of Experimental Pathology, Pisa,(More)
We previously reported that in a diabetes mouse model, characterised by moderate hyperglycaemia and reduced β-cell mass, the radical scavenger bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate di-hydrochloride (IAC), a non-conventional cyclic hydroxylamine derivative, improves metabolic alterations by counteracting β-cell dysfunction associated(More)
OBJECTIVE This study analyzed histological and histochemical features of specimens of the orbicularis oris muscle, and palatal and pharyngeal muscles biopsied during surgery from 33 patients affected by cleft lip and palate. DESIGN Three groups were studied: 20 patients affected by cleft palate with or without cleft lip (at the time of primary(More)
  • 1