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- Nunziata Morabito, Alessandra Crisafulli, +10 authors Francesco Squadrito
- Journal of bone and mineral research : the…
- 2002
The natural isoflavone phytoestrogen genistein has been shown to stimulate osteoblastic bone formation, inhibit osteoclastic bone resorption, and prevent bone loss in ovariectomized rats. However, no… (More)
- Herbert Marini, Letteria Minutoli, +15 authors Francesco Squadrito
- Annals of internal medicine
- 2007
BACKGROUND
Observational studies and small trials of short duration suggest that the isoflavone phytoestrogen genistein reduces bone loss, but the evidence is not definitive.
OBJECTIVE
To assess… (More)
- Alessandra Crisafulli, Herbert Marini, +10 authors Francesco Squadrito
- Menopause
- 2004
OBJECTIVE
We evaluated and compared the effects of the phytoestrogen genistein, estrogen-progestogen therapy (EPT), and placebo on hot flushes and endometrial thickness in postmenopausal women.
… (More)
- Rosario D'Anna, Maria Letizia Cannata, +13 authors Francesco Squadrito
- Menopause
- 2007
OBJECTIVE
To evaluate in a 12-month, prospective, randomized, double-blind, placebo-controlled study whether pure administration of the phytoestrogen genistein (54 mg/d) might reduce the number and… (More)
- Marco Atteritano, Herbert Marini, +15 authors Francesco Squadrito
- The Journal of clinical endocrinology and…
- 2007
CONTEXT
Genistein, a soy isoflavone, has received wide attention over the last few years because of its potential preventive role for cardiovascular disease.
OBJECTIVE
Our objective was to assess… (More)
- Herbert Marini, Alessandra Bitto, +19 authors Francesco Squadrito
- The Journal of clinical endocrinology and…
- 2008
CONTEXT
Genistein aglycone improves bone metabolism in women. However, questions about the long-term safety of genistein on breast as well as its continued efficacy still remain.
OBJECTIVE
We… (More)
- Nunziata Morabito, Agostino Gaudio, +7 authors Nicola Frisina
- Journal of bone and mineral research : the…
- 2004
UNLABELLED
Osteoporosis represents an important cause of morbidity in adult thalassemic patients, and its pathogenesis has not, as yet, been completely clarified. In our study, we observed that… (More)
- Francesco Squadrito, Domenica Altavilla, +8 authors Giovanni Squadrito
- The American journal of medicine
- 2003
PURPOSE
Genistein, a phytoestrogen found in soybeans, corrects endothelial dysfunction induced by oophorectomy in animals. Using a double-blind, controlled, randomized design, we evaluated its… (More)
- Maria R Buemi, D. Marino, +8 authors Francesco Corica
- Nephron
- 2001
The effect of a static magnetic field (MF) of 0.5 mT of intensity on the cell proliferation/cell death balance was investigated in renal cells (VERO) and cortical astrocyte cultures from rats.… (More)
- Nunziata Morabito, Giuseppina T Russo, +10 authors Nicola Frisina
- Bone
- 2007
Osteoporosis affects approximately 40-50% of adult patients with beta-Thalassemia Major (beta TM). Recent data have implicated an altered modulation of the osteoprotegerin (OPG)/receptor activator of… (More)