Nick Peacock

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The Lese are subsistence farmers living in the Ituri Forest of north-east Zaïre. They exhibit significant birth seasonality, with lowest frequencies of conception when food production is least, nutritional status is low and ovarian function, as measured by salivary steroid hormone levels, is reduced. Efe pygmy foragers, who live in the same geographical(More)
Ovarian function is examined in 35 Lese women inhabiting the Ituri Forest of northeastern Zaire over a period of 4 months through measurements of progesterone in saliva samples collected twice weekly. Ovulatory frequency is found to be only 56% on average, with a pattern of age variation similar to that observed in western women, though lower in level at(More)
We assessed the nutritional status of 90 pygmies (Efe) and 211 members of a neighboring horticultural Lese in the Ituri forest in northeast Zaire. Clinical signs of iron and iodine deficiency were highly prevalent, but the frequency of these and other clinical signs of nutritional deficiency did not differ between the two groups. Infectious diseases such as(More)
30 Ituri women (Zaire) -- 14 Efe and 16 Balese -- were targeted as subjects in this study designed to verify that, under field conditions, the salivary steroid method can reliably discern follicular and luteal levels of progesterone in normal menstrual cycles and to examine the hypothesis that infertility among these women is due to tubal factors. Findings(More)
Antagonist analogues of gonadotropin-releasing hormone (GnRH-A) alone inhibit spermatogenesis in experimental animals, but concomitant decline in serum testosterone leads to abolition of mating behavior. We assessed if the antifertility effects of GnRH-A could be dissociated from its effects on mating behavior by combining it with a small dose of androgen.(More)
The testosterone dose-dependency of several mating and nonmating behaviors was examined in the male rat, chemically castrated with a GnRH antagonist analog. Graded doses of testosterone enanthate (TE) were given to male rats to reinstate behaviors abolished by GnRH antagonist treatment. GnRH antagonist treatment alone markedly lowered serum LH, FSH and T(More)
BACKGROUND Sex disparities in the diagnosis and treatment of chest pain or suspected angina have been demonstrated in multiple clinical settings. Out-of-hospital (OOH) care for chest pain is protocol-driven and may be less likely to demonstrate differences between men and women. OBJECTIVES The objectives were to investigate the relationship between sex(More)
This study examined the pharmacokinetics (the time course and pattern of testosterone release) and pharmacodynamics (effects on accessory sex organ weights, and serum LH and FSH levels) of a biodegradable testosterone microsphere formulation in the male rat. Two hundred seventy-five 55-day-old, sexually mature male rats underwent surgical orchiectomy or(More)
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