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Opioid action was thought to exert reinforcing effects solely via the initial agonism of opioid receptors. Here, we present evidence for an additional novel contributor to opioid reward: the innate immune pattern-recognition receptor, toll-like receptor 4 (TLR4), and its MyD88-dependent signaling. Blockade of TLR4/MD2 by administration of the nonopioid,(More)
Photometry is used as a cheap and easy way to estimate redshifts of galaxies, which would otherwise require considerable amounts of expensive telescope time. However, the analysis of photometric redshift datasets is a task where it is sometimes difficult to achieve a high classification accuracy. This work presents a custom Genetic Algorithm (GA) for mining(More)
This paper presents a framework for identifying the legal risks associated with performing network forensics on public networks. The framework is discussed in the context of the Gnutella P2P network protocol for which the legal issues related to authorized access have not yet been addressed. 1. Introduction The analysis of legal issues related to(More)
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