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Experiments were performed with intact human red blood cells to determine whether the inhibitory effects of high Cl- concentrations on Cl- exchange are primarily due to interaction at the cytoplasmic or the external surface of the membrane. When internal Cl- was varied from 150 mM to 600 mM Cl- (using the nystatin technique), keeping external Cl- constant(More)
Niflumic acid is a noncompetitive inhibitor of chloride exchange, which binds to a site different from the transport or modifier sites. When the internal Cl- concentration is raised, at constant extracellular Cl-, the inhibitory potency of niflumic acid increases. This effect cannot be attributed to changes in membrane potential, but rather it suggests that(More)
In this paper, we introduce a direct manipulation tabletop multi-touch user interface for spatial audio scenes. Although spatial audio rendering exists for several decades now, mass market applications have not been developed and the user interfaces still address a small group of expert users. We implemented an easy-to-use direct manipulation interface for(More)
The influence of physical factors on the mechanical impedance at the palmar surface of the finger have been investigated. The studies were conducted with 12 subjects using random vibration over the frequency range 10 to 1000 Hz. It was found that increase in contact force (from 0.25 to 8 N) caused large increases in the modulus of the point mechanical(More)
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