Nicholas Stiffler

Publications11
h-index8
Citations1,534
Highly Influential Citations135
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Population Genomics of Parallel Adaptation in Threespine Stickleback using Sequenced RAD Tags
Next-generation sequencing technology provides novel opportunities for gathering genome-scale sequence data in natural populations, laying the empirical foundation for the evolving field of… Expand
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Use of Illumina sequencing to identify transposon insertions underlying mutant phenotypes in high-copy Mutator lines of maize.
High-copy transposons have been effectively exploited as mutagens in a variety of organisms. However, their utility for phenotype-driven forward genetics has been hampered by the difficulty of… Expand
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POGs/PlantRBP: a resource for comparative genomics in plants
TLDR
POGs/PlantRBP clusters proteins in the rice and Arabidopsis proteomes into putative orthologous groups based on a mutual-best-hit-strategy, with POG assignments subsequently evaluated by phylogenetic analysis. Expand
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Large-scale genetic analysis of chloroplast biogenesis in maize.
BACKGROUND Chloroplast biogenesis involves a collaboration between several thousand nuclear genes and ~100 genes in the chloroplast. Many of the nuclear genes are of cyanobacterial ancestry and… Expand
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POGs2: A Web Portal to Facilitate Cross-Species Inferences About Protein Architecture and Function in Plants
The Putative orthologous Groups 2 Database (POGs2) (http://pogs.uoregon.edu/) integrates information about the inferred proteomes of four plant species (Arabidopsis thaliana, Zea mays, Orza sativa,… Expand
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Rapid mapping and identification of mutations in C. elegans by RAD mapping and genomic interval pull-down sequencing
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High-Density Detection of Restriction-Site-Associated DNA Markers for Rapid Mapping of Mutated Loci in Neurospora
The wealth of sequence information available for Neurospora crassa and other fungi has greatly facilitated evolutionary and molecular analyses of this group. Although “reverse” genetics, in which… Expand
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Rapid Mapping and Identification of Mutations in Caenorhabditis elegans by Restriction Site-Associated DNA Mapping and Genomic Interval Pull-Down Sequencing
Forward genetic screens provide a powerful approach for inferring gene function on the basis of the phenotypes associated with mutated genes. However, determining the causal mutation by traditional… Expand
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Ribosome Profiling in Maize.
Ribosome profiling (also known as Ribo-seq) provides a genome-wide, high-resolution, and quantitative accounting of mRNA segments that are occupied by ribosomes in vivo. The method has been used to… Expand
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Epigenetic loss of heterozygosity of Apc and an inflammation-associated mutational signature detected in Lrig1+/−-driven murine colonic adenomas
The loss of a single copy of adenomatous polyposis coli (Apc) in leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1)-expressing colonic progenitor cells induces rapid growth of adenomas in… Expand