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  • M. Dudley, J. Wunderlich, +18 authors S. Rosenberg
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2005 (First Publication: 1 April 2005)
  • PURPOSE We investigated the combination of lymphodepleting chemotherapy followed by the adoptive transfer of autologous tumor reactive lymphocytes for the treatment of patients with refractoryExpand
  • Mark E. Dudley, James Chih‐Hsin Yang, +17 authors Steven A Rosenberg
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2008 (First Publication: 10 November 2008)
  • PURPOSE The two approved treatments for patients with metastatic melanoma, interleukin (IL)-2 and dacarbazine, mediate objective response rates of 12% to 15%. We previously reported that adoptiveExpand
  • Willem W. Overwijk, Marc Robert Theoret, +15 authors Nicholas P. Restifo
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2003 (First Publication: 18 August 2003)
  • Many tumor-associated antigens are derived from nonmutated “self” proteins. T cells infiltrating tumor deposits recognize self-antigens presented by tumor cells and can be expanded in vivo withExpand