The pattern of cancer in African gold miners over the 8-year period 1964-71, comprising 2,926,461 man-years of employment was studied. Of the 1344 cancers found, primary liver cancer accounted for 52-8%, oesophageal cancer 12-1%, cancer of the respiratory system 5-4% and cancer of the bladder 4-8%. Analysis of the spatial distribution of these four cancers,… (More)
Data on the incidence of cancer of the oesophagus in the Transkei for years 1965-69 are presented, age specific rates for the sexes discussed and the spatial relationship of well-defined regions of the high and low incidence demonstrated.
As an extension of an earlier study covering the 8-year period 1965-71 (t1), the incidence of cancer in black gold miners over a second 8-year period, 1972-79 (t2) has been investigated. The population again totalled 2.9 million man-years of employment, an average of 363,800 men per year. Of the 903 cancers found in t2, primary liver cancer accounted for… (More)
Mortality data on lung cancer among the black populations of South Africa, newly available from the first ever nation-wide enumerations, are analysed for age-specific rates and significant geographical and intertribal variations. This study finds a higher incidence at younger ages than among whites, an urban excess similar to other population groups in… (More)
The 5-year study of cancer in black gold miners, 1964-68, previously reported (Robertson et al., 1971) has now been extended for a separate 8-year period, 1972-79. This allows analyses of all cancers together and of 6 less common sites of cancer severally: lymphosarcomas, colon and rectum, leukaemia, stomach, pancreas and buccal cavity and also of those too… (More)
Dissolution dynamic nuclear polarization (DNP) enables the metabolism of hyperpolarized (13)C-labelled molecules, such as the conversion of [1-(13)C]pyruvate to [1-(13)C]lactate, to be dynamically and non-invasively imaged in tissue. Imaging of this exchange reaction in animal models has been shown to detect early treatment response and correlate with… (More)
We describe here the results of the final 8 years of geographical and temporal data of a 33-year study of the cancer experience of 12.8 million man-years of black miners working on the gold fields of South Africa over the period 1964-96. These workers were recruited from 15 territories, the major areas during the most recent period being Lesotho (26.8%),… (More)