Nicholas Lynch

Michal Hetman2
Bridgit E Morris1
Justin Hallgren1
2Michal Hetman
1Bridgit E Morris
1Justin Hallgren
1Nicholas Mcchesney Lynch
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The nucleolus serves as a principal site of ribosome biogenesis but is also implicated in various non-ribosomal functions, including negative regulation of the pro-apoptotic transcription factor p53. Although disruption of the nucleolus may trigger the p53-dependent neuronal death, neurotoxic consequences of a selective impairment of ribosome production are(More)
Lynch, Nicholas McChesney, "Role of ribosomal biogenesis in axonal morphogenesis." (2015). ABSTRACT Elongating axons require a host of macromolecules for outgrowth. The importance of lipid, protein, and general RNA synthesis for initial axonal growth has been previously investigated, but the role of rRNA synthesis and ribosome production in axonal(More)
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