Nicholas J. Long

Clare Bakewell2
Charlotte Rivas2
Juan Gallo2
Florencia Minuzzi2
Guy A. Rutter1
2Clare Bakewell
2Charlotte Rivas
2Juan Gallo
2Florencia Minuzzi
1Guy A. Rutter
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MRI offers high spatial resolution with excellent tissue penetration but it has limited sensitivity and the commonly administered contrast agents lack specificity. In this study, two sets of iron oxide nanoparticles (IONPs) were synthesized that were designed to selectively undergo copper-free click conjugation upon sensing of matrix metalloproteinase (MMP)(More)
We present large-scale reproducible fabrication of multifunctional ultrasharp metallic structures on planar substrates with capabilities including magnetic field nanofocusing and plasmonic sensing. Objects with sharp tips such as wedges and pyramids made with noble metals have been extensively used for enhancing local electric fields via the lightning-rod(More)
Despite the contribution of changes in pancreatic β-cell mass to the development of all forms of diabetes mellitus, few robust approaches currently exist to monitor these changes prospectively in vivo. Although magnetic-resonance imaging (MRI) provides a potentially useful technique, targeting MRI-active probes to the β cell has proved challenging. Zinc(More)
Iso-selective initiators for the ring-opening polymerization (ROP) of rac-lactide are rare outside of Group 13. We describe the first examples of highly iso-selective lutetium initiators. The phosphasalen lutetium ethoxide complex shows excellent iso-selectivity, with a P(i) value of 0.81-0.84 at 298 K, excellent rates, and high degrees of polymerization(More)
Maximum entropy inference can be used to find equations for the critical currents (J c) in a type II superconductor as a function of temperature, applied magnetic field, and angle of the applied field, θ or . This approach provides an understanding of how the macroscopic critical currents arise from averaging over different sources of vortex pinning. The(More)
Two novel dual-modal MRI/optical probes based on a rhodamine-DO3A conjugate have been prepared. The bis(aqua)gadolinium(III) complex Gd.L1 and mono(aqua)gadolinium(III) complex Gd.L2 behave as dual-modal imaging probes (r1 = 8.5 and 3.8 mM(-1) s(-1) for Gd.L1 and Gd.L2, respectively; λex = 560 nm and λem = 580 nm for both complexes). The rhodamine fragment(More)
The synthesis and characterization of a series of 8-quinolinolato gallium complexes is presented, and the complexes are analogous to a series of aluminum complexes previously reported. The complexes have been shown to be active initiators for the ring-opening polymerization of rac-lactide. High degrees of polymerization control are demonstrated, as(More)
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