Nicholas Gibbs

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The extent of tumour growth beyond the muscularis propria (mesorectal spread) was measured in specimens from 167 consecutive patients with rectal cancer. The 5-year survival was significantly greater in patients with slight mesorectal spread (4 mm or less) than in those with more extensive mesorectal spread (55% [95% confidence interval 42-66%] vs 25%(More)
Networked systems still suffer from poor firewall configuration and monitoring. VisualFirewall seeks to aid in the configuration of firewalls and monitoring of networks by providing four simultaneous views that display varying levels of detail and timescales as well as correctly visualizing firewall reactions to individual packets. The four implemented(More)
An antibody, 21N, raised against a synthetic peptide from the predicted sequence of the c-erbB-2 protein has been used immunocytochemically in a retrospective study of formalin fixed paraffin embedded breast biopsies. Fourteen out of 103 infiltrating ductal carcinomas exhibited positive membrane staining. Fifty-four of these tumours had lymph node(More)
The effect of halothane on hemodynamic responses to noxious stimuli was investigated in anesthetized male Sprague-Dawley rats. It was found that increasing the end-tidal halothane concentration from sub-MAC to supra-MAC levels was frequently associated with a reversal of the mean arterial pressure response to a noxious stimulus from a pressor response to(More)
The effect of atracurium-vecuronium combinations on the onset and duration of neuromuscular blockade was investigated in 30 adult patients undergoing general anaesthesia for elective surgery. The patients were randomized to receive either atracurium 0.6 mg.kg-1, vecuronium 0.1 mg.kg-1, or quarter-dose, half-dose, or full-dose combinations of the two drugs.(More)
The effect of neuromuscular blockade with vecuronium on the hemodynamic responses to a noxious stimulus was investigated in male Sprague-Dawley rats. The rats were anesthetized with either halothane (group 1, n = 10), or isoflurane (group 2, n = 10). The maximum values for heart rate and mean arterial pressure during the noxious stimulus (base-tail clamp)(More)
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