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  • Nicholas G. Housden, Steven R Loftus, Geoffrey R. Moore, Richard P. James, Colin Kleanthous
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Published: 27 September 2005)
  • Binding of enzymatic E colicins to the vitamin B12 receptor, BtuB, is the first stage in a cascade of events that culminate in the translocation of the cytotoxic nuclease into the Escherichia coliContinue Reading
  • Marc Graille, Enrico A Stura, +7 authors J. B. Charbonnier
  • Biology, Medicine
  • Structure
  • 2001 (First Published: 1 August 2001)
  • BACKGROUND Peptostreptococcus magnus protein L (PpL) is a multidomain, bacterial surface protein whose presence correlates with virulence. It consists of up to five homologous immunoglobulin bindingContinue Reading
  • Nicholas G. Housden, Justyna Aleksandra Wojdyla, +4 authors Colin Kleanthous
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2010 (First Published: 14 December 2010)
  • The porins OmpF and OmpC are trimeric β-barrel proteins with narrow channels running through each monomer that exclude molecules > 600 Da while mediating the passive diffusion of small nutrients andContinue Reading
  • Nicholas G. Housden, Steven Harrison, +7 authors Michael G. Gore
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 2004 (First Published: 5 March 2004)
  • Detailed stopped-flow studies in combination with site-directed mutagenesis, isothermal titration calorimetry data and x-ray crystallographic knowledge have revealed that the biphasic pre-equilibriumContinue Reading
  • Renée Ménez, Nicholas G. Housden, Stephen Harrison, Colette Jolivet-Reynaud, Michael G. Gore, Enrico A Stura
  • Chemistry, Medicine
  • Acta crystallographica. Section D, Biological…
  • 2005 (First Published: 1 June 2005)
  • Proteins and peptides with variable degrees of disorder are a challenge for protein crystallization. These may be completely disordered or just contain regions with a high degree of mobility that mayContinue Reading