Nicholas F Prayson

Learn More
The purpose of this study is to determine whether anaplastic astrocytoma patients with intratumoral vascular thrombi have a worse survival than anaplastic astrocytoma patients without thrombi. A retrospective review of 101 patients (60 males; mean age, 53.3 years) with anaplastic astrocytoma (World Health Organization grade III) was conducted. Thrombi were(More)
Tissue inhibitors of metalloproteinases (TIMPs) while originally characterized as inhibitors of matrix metalloproteinases (MMPs) have recently been shown to have a wide range of functions that are independent of their MMP inhibitory properties. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a potent inhibitor of VEGF-mediated angiogenesis and(More)
Patients with glioblastoma multiforme (GBM) are known to be at risk for hypercoagulable events. Tumoral intravascular thrombi likely contribute to the development of hypoxia and necrosis. The purpose of this study was to assess whether there is a relationship between the number of thrombi identified microscopically at the time of tumor resection and the(More)
OBJECTIVES To determine the rates of infection in low-energy gunshot wounds (GSWs) to the extremity. DESIGN Retrospective review. SETTING Level I trauma center. PATIENTS/PARTICIPANTS Patients (N = 140) with at least 90-day follow-up for extremity-only low-energy GSW injuries from 2010-2014 were retrospectively reviewed. Treatment was recorded,(More)
OBJECTIVES The purpose of this study is to characterize the demographics, interventions, infection rates, and other complications after intra-articular (IA) gunshot wounds. DESIGN Retrospective review. SETTING Level I trauma center. PATIENTS/PARTICIPANTS Fifty-three patients with 55 civilian low-velocity IA gunshot injuries with a minimum of 4 weeks(More)
  • 1