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Virtual environments (VEs) allow users to experience and interact with a rich sensory environment, but most virtual worlds contain only sensory information similar to that which we experience in the physical world. <i>Information-rich</i> virtual environments (IRVEs) combine the power of VEs and information visualization, augmenting VEs with additional(More)
! Abstract— Three-dimensional user interfaces (3D UIs) support user tasks in many non-traditional interactive systems such as virtual environments and augmented reality. Although 3D UI researchers have been successful in identifying basic user tasks and interaction metaphors, evaluating the usability of 3D interaction techniques, and improving the usability(More)
In recent years, consumers have witnessed a technological revolution that has delivered more-realistic experiences in their own homes. Expanding technologies have provided larger displays with higher resolutions, faster refresh rates, and stereoscopic capabilities. These advances have increased the level of display fidelity—the objective degree of exactness(More)
Epstein-Barr virus (EBV) is an important human pathogen that establishes a life-long persistent infection and for which no precise animal model exists. In this paper, we describe in detail an agent-based model and computer simulation of EBV infection. Agents representing EBV and sets of B and T lymphocytes move and interact on a three-dimensional grid(More)
Information-rich virtual environments (IRVEs) have been described as environments in which perceptual information is enhanced with abstract (or symbolic) information, such as text, numbers, images, audio, video, or hyperlinked resources. Desktop virtual environment (VE) applications present similar information design and layout challenges as immersive VEs,(More)
Recent Standards specifications offer important but underemployed techniques to maximize access-to and distribution-of information for real-time 3D visualization over the web. This paper describes and evaluates such techniques to transform structured data such as Chemical Markup Language (CML) to different forms and contexts for Web3D delivery using(More)
Design patterns capture reusable solutions to common problems, and have been used as an approach to simplifying the development and maintenance of software systems. This paper extracts several design patterns from the implementations of recent popular 3D Visualization toolkits. While these toolkits follow the same X3D standard, their respective realizations(More)
This paper reports on the work of the Web3D Consortium's Medical Working Group to specify and implement MedX3D -- an extension to the X3D standard that will support advanced medical visualization functionality and medical data exchange. This initiative covers volume rendering, ontology support, and data import/export, for standalone applications and(More)
This paper describes our recent experimental evaluation of Information-Rich Virtual Environment (IRVE) interfaces. To explore the depth cue/visibility tradeoff between annotation schemes, we design and evaluate two information layout techniques to support search and comparison tasks. The techniques provide different depth and association cues between(More)
The possibility of using computer simulation and mathematical modeling to gain insight into biological and other complex systems is receiving increased attention. However, it is as yet unclear to what extent these techniques will provide useful biological insights or even what the best approach is. Epstein-Barr virus (EBV) provides a good candidate to(More)