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  • O. Ziv, N. Geacintov, S. Nakajima, A. Yasui, Z. Livneh
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2009 (First Publication: 14 July 2009)
  • Human cells tolerate UV-induced cyclobutane pyrimidine dimers (CPD) by translesion DNA synthesis (TLS), carried out by DNA polymerase η, the POLH gene product. A deficiency in DNA polymerase η due toExpand
  • Sharon Avkin, Moshe Goldsmith, Susana Velasco-Miguel, Nicholas E. Geacintov, Errol C. Friedberg, Zvi Livneh
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2004 (First Publication: 17 December 2004)
  • Replication across unrepaired DNA lesions in mammalian cells is effected primarily by specialized, low fidelity DNA polymerases. We studied translesion DNA synthesis (TLS) across aExpand
  • Olga Rechkoblit, Yanbin Zhang, +5 authors Nicholas E. Geacintov
  • Chemistry, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 23 August 2002)
  • The effectiveness of in vitro primer elongation reactions catalyzed by human bypass DNA polymerases κ (hDinB1), pol η (hRad30A), pol ι (hRad30B), and yeast pol ζ (Rev3 and Rev7) in site-specificallyExpand