Learn More
BACKGROUND The prevalence of obesity has increased substantially over the past 30 years. We performed a quantitative analysis of the nature and extent of the person-to-person spread of obesity as a possible factor contributing to the obesity epidemic. METHODS We evaluated a densely interconnected social network of 12,067 people assessed repeatedly from(More)
centered on a large database, but in this case it is entirely of living organisms, the marine bivalves. Over 28,000 records of bivalve gen-era and subgenera from 322 locations around the world have now been compiled by these authors, giving a global record of some 854 genera and subgenera and 5132 species. No fossils are included in the database, but(More)
BACKGROUND The prevalence of smoking has decreased substantially in the United States over the past 30 years. We examined the extent of the person-to-person spread of smoking behavior and the extent to which groups of widely connected people quit together. METHODS We studied a densely interconnected social network of 12,067 people assessed repeatedly from(More)
OBJECTIVES To evaluate whether happiness can spread from person to person and whether niches of happiness form within social networks. DESIGN Longitudinal social network analysis. SETTING Framingham Heart Study social network. PARTICIPANTS 4739 individuals followed from 1983 to 2003. MAIN OUTCOME MEASURES Happiness measured with validated four item(More)
Social networks exhibit strikingly systematic patterns across a wide range of human contexts. Although genetic variation accounts for a significant portion of the variation in many complex social behaviors, the heritability of egocentric social network attributes is unknown. Here, we show that 3 of these attributes (in-degree, transitivity, and centrality)(More)
The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing correlations obtained from the disease history of more than 30 million patients in a Phenotypic Disease Network (PDN). We present(More)
Current methods for the detection of contagious outbreaks give contemporaneous information about the course of an epidemic at best. It is known that individuals near the center of a social network are likely to be infected sooner during the course of an outbreak, on average, than those at the periphery. Unfortunately, mapping a whole network to identify(More)
For repeated events, fixed-effects regression methods—which control for all stable covariates—can be implemented by doing Cox regression with stratification on individuals. For nonrepeated events, we consider the use of conditional logistic regression to estimate fixed-effects models with discrete-time data. Known in the epidemiological literature as the(More)