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As it has been generally reported that oppositely charged cationic liposomes (CLs) are superior to either neutral or anionic liposomes as gene delivery carrier, interest in the properties, structures, transfection mechanism of CLs and so forth arises unprecedentedly. However, our understanding about the mechanism of CLs-gene complexes (lipoplex)-cell(More)
Monodisperse magnetic iron oxide nanoparticles (MNPs), coated with PEG at different molecular weight, were prepared via self-assembly method. The particle diameters were measured by dynamic light scattering and transmission electron microscope. Increasing the molecular weight of PEG in the coating polymer increased the overall particles diameter. As coating(More)
Due to the frequent consumption of capsaicin (CAP) and its current therapeutic application, the correct assessment of this compound is important from a public health standpoint. The purpose of this study was to find out whether CAP affects rat cytochrome P450 (CYP) enzymes (CYP1A2, CYP2C19, and CYP3A4) by using cocktail probe drugs in vivo. A cocktail(More)
Study Hypothesis A large fraction of mammalian genomes is transcribed into noncoding RNAs. Despite the prevalence in the genome, up until recently, noncoding RNAs were regarded as junk RNAs that do not code for protein and, thereby, have no biological purpose. However, over the past decade, it has become increasingly evident that noncoding RNAs can and do(More)
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