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BAP31 is an endoplasmic reticulum protein-sorting factor that associates with newly synthesized integral membrane proteins and controls their fate (i.e., egress, retention, survival, or degradation). BAP31 is itself an integral membrane protein and a constituent of several large protein complexes. Here, we show that a part of the BAP31 population interacts(More)
The main challenge in an automated diagnostic system for the early diagnosis of melanoma is the correct segmentation and classification of moles, often occluded by hair in images obtained with a dermoscope. Hair occlusion causes segmentation algorithms to fail to identify the correct nevus border, and can cause errors in estimating texture measures. We(More)
Circulating 25-hydroxyvitamin D (25-OHD) is associated with a reduction in risk of some cancers, but its association with prognosis among patients with cancer is poorly understood. In view of the increasing number of cancer survivors in the United States and the high prevalence of vitamin D deficiency among patients with cancer, an evaluation of the role of(More)
—DICOM specifies that digital data values should be linearly mapped to just-noticable differences (JNDs) in luminance. Increasing the number of JNDs available requires increasing the display's dynamic range. However, operating over too wide a range may cause human observers to miss contrast in dark regions due to adaptation to bright areas or,(More)
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