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The application of a transfer function model (TFM) in a real-time dynamic traffic assignment system is investigated. The motivation is to improve the speed estimation method to enable better system consistency with reality in real-time operation. The study is conducted by adopting a TFM derived from actual detector data in San Antonio, Texas. This model is(More)
OBJECTIVES Arginine is converted in the endothelial cells to nitric oxide (NO) and citrulline. NO is a potent vasodilator in humans, but diabetics may have a reduced generation of NO which results in endothelial dysfunction. The aim of this study was to evaluate the effects of oral arginine on nitric oxide production, counter-regulatory hormones and blood(More)
PURPOSE Current models of mechanical intestinal lengthening employ a single device in an isolated segment. Here we demonstrate that polycaprolactone (PCL) springs can be deployed in-series to lengthen multiple intestinal segments simultaneously to further increase overall intestinal length. METHODS A Roux-en-y jejunojejunostomy with a blind Roux limb was(More)
PURPOSE Distraction enterogenesis has been investigated as a novel treatment for patients with short bowel syndrome (SBS) but has been limited by loss of intestinal length during restoration and need for multiple bowel surgeries. The feasibility of in-continuity, spring-mediated intestinal lengthening has yet to be demonstrated. METHODS Juvenile(More)
BACKGROUND Misdiagnosing appendicitis may lead to unnecessary surgery. The study evaluates the risk factors for negative appendectomies, as well as the clinical and socioeconomic consequences of negative appendectomy across three states. MATERIALS AND METHODS Data were obtained from the California, New York, and Florida State Inpatient Databases(More)
Macromolecular complexes and organelles play crucial roles within cells, but their native architectures are often unknown. Here, we use an evolutionarily conserved germline organelle, the germ granule, as a paradigm. In Drosophila embryos, we map one of its interactomes using a novel in vivo crosslinking approach that employs two interacting granule(More)
INTRODUCTION Techniques of distraction enterogenesis have been explored to provide increased intestinal length to treat short bowel syndrome (SBS). Self-expanding, polycaprolactone (PCL) springs have been shown to lengthen bowel in small animal models. Their feasibility in larger animal models is a critical step before clinical use. METHODS Juvenile(More)
We search for cavitation in tumescent subcutaneous tissue of a live pig under application of pulsed, 1-MHz ultrasound at 8 W cm-2 spatial peak and pulse-averaged intensity. We find no evidence of broadband acoustic emission indicative of inertial cavitation. These acoustic parameters are representative of those used in external-ultrasound-assisted(More)
Spam is a problem that refuses to go away. An immense amount of time and money is currently devoted to hiding spam, but not enough is devoted to effectively preventing it. CAPTCHAs are a prevalent spam prevention mechanism, but are getting harder for humans to solve and easier for programs to "break". CAPTCHAs also cannot prevent spam from hijacked accounts(More)
BACKGROUND Distraction enterogenesis has been investigated as a novel treatment for short bowel syndrome (SBS). With variable intestinal sizes, it is critical to determine safe, translatable spring characteristics in differently sized animal models before clinical use. Nitinol springs have been shown to lengthen intestines in rats and pigs. Here, we show(More)