Pierre Bravetti3
Pablo Maureira2
Annie Marc2
Caroline Ferrari2
3Pierre Bravetti
2Pablo Maureira
2Annie Marc
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BACKGROUND In the bone marrow, hematopietic and mesenchymal stem cells form a unique niche in which the oxygen tension is low. Hypoxia may have a role in maintaining stem cell fate, self renewal and multipotency. However, whereas most studies addressed the effect of transient in vitro exposure of MSC to hypoxia, permanent culture under hypoxia should(More)
We consider the problem of migrating user data between data centers. We introduce distributed storage overlays, a simple abstraction that represents data as stacked layers in different places. Overlays can be readily used to cache data objects, migrate these caches, and migrate the home of data objects. We implement overlays as part of a key-value object(More)
  • Patrice Gallet, Bérengère Phulpin, Jean-Louis Merlin, Agnès Leroux, Pierre Bravetti, Hinda Mecellem +2 others
  • 2011
PURPOSE Beside its efficacy in cancer treatment, radiotherapy induces degeneration of healthy tissues within the irradiated area. The aim of this study was to analyze the variations of proinflammatory (IL-1α, IL-2, IL-6, TNF-α, IFN-γ), profibrotic (TGF-β1), proangiogneic (VEGF) and stem cell mobilizing (GM-CSF) cytokines and growth factors in an animal(More)
  • Patrick Meybohm, Matthias Gruenewald, Martin Albrecht, Kai D. Zacharowski, Ralph Lucius, Karina Zitta +4 others
  • 2009
BACKGROUND Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear. This study sought to examine whether hypothermia and the combination of hypothermia and pharmacological postconditioning are cardioprotective in a model of(More)
Tissue engineering scaffold constitutes a new strategy of myocardial repair. Here, we studied the contribution of a patch using autologous mesenchymal stem cells (MSCs) seeded on collagen-1 scaffold on the cardiac reconstruction in rat model of chronic myocardial infarction (MI). Patches were cultured with controlled MSCs (growth, phenotype and(More)
  • Klemens König, David Köhler, Tiago Granja, Carla Jennewein, Nguyen Tran, Valbona Mirakaj +2 others
  • 2012
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of UNC5B during an acute inflammatory response we investigated the role of UNC5B on acute hepatic IRI. We report(More)
BACKGROUND The teaching of implant surgery, as in other medical disciplines, is currently undergoing a particular evolution. AIM OF THE STUDY To assess the usefulness of haptic device, a simulator for learning and training to accomplish basic acts in implant surgery. MATERIALS AND METHODS A total of 60 people including 40 third-year dental students(More)
BACKGROUND We aimed to explore (i) the short-term retention of intramedullary implanted mesenchymal stem cells BMSCs and (ii) their impact on the bone blood flow and metabolism in a rat model of hindlimb irradiation. METHODS Three months after 30 Gy irradiation, fourteen animals were referred into 2 groups: a sham-operated group (n = 6) and a treated(More)