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  • Jo S, H R V O L P I C E L L I, +5 authors A A V O L P I C E L L I
  • 2014
There currently is a great demand for effective medications to reduce the high relapse rates that occur in the early stages of treatment for alcohol dependence. Recent clinical trials of the opiate antagonist naltrexone have shown that this medication significantly decreases excessive alcohol drinking. A l t h o u g h c u rr en t t r e a t m e nt s f o r a(More)
Uncertainties associated with pesticide exposure forecasts arise from many sources such as spatial and temporal variability of factors influencing pesticide behavior, inaccuracies in the measurement or estimation of input parameters and deficiencies in model structure. It is well acknowledged that, at least to some extent, simulation uncertainties should be(More)
Nicotinamide phosphoribosyltransferase (NAMPT) is a pleiotropic protein that functions as an enzyme, cytokine, growth factor and hormone. As a target for oncology, NAMPT is particularly attractive, because it catalyzes the rate-limiting step in the salvage pathway to generate nicotinamide adenine dinucleotide (NAD), a universal energy- and signal-carrying(More)
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