Newman Osafo | Semantic Scholar

Publications
Influence

Aqueous ethanol extract of the fruit of Xylopia aethiopica (Annonaceae) exhibits anti-anaphylactic and anti-inflammatory actions in mice.

David Darko Obiri, Newman Osafo

Medicine

Journal of ethnopharmacology

2013 (First Publication: 30 July 2013)

ETHNOPHARMACOLOGICAL RELEVANCE Xylopia aethiopica has been traditionally used in the form of the dried fruit decoction to treat bronchitis, asthma, arthritis and rheumatism in Ghana, Nigeria and… Expand

Phytochemical and Pharmacological Review of Cryptolepis sanguinolenta (Lindl.) Schlechter

Newman Osafo, Kwesi Boadu Mensah, Oduro Kofi Yeboah

Medicine

Advances in pharmacological sciences

2017 (First Publication: 15 October 2017)

Ethnopharmacological Relevance Cryptolepis sanguinolenta is a scrambling thin-stemmed shrub found in Africa. Traditionally in West Africa, it is employed in the treatment of malaria, diarrhea, and… Expand

Xylopia aethiopica (Annonaceae) fruit extract suppresses Freund's adjuvant-induced arthritis in Sprague-Dawley rats.

David Darko Obiri, Newman Osafo, Patrick George Ayande, Aaron Opoku Antwi

Medicine

Journal of ethnopharmacology

2014 (First Publication: 28 March 2014)

ETHNOPHARMACOLOGICAL RELEVANCE Xylopia aethiopica is used in a decoction of the dried fruit to treat bronchitis, asthma, arthritis, rheumatism, headache, neuralgia and colic pain. The aim of the… Expand

Stigmasterol Modulates Allergic Airway Inflammation in Guinea Pig Model of Ovalbumin-Induced Asthma

Aaron Opoku Antwi, David Darko Obiri, Newman Osafo

Medicine

Mediators of inflammation

2017 (First Publication: 5 May 2017)

We explored the potential benefits of stigmasterol in the treatment of asthma, an airway disorder characterized by immune pathophysiology and with an ever-increasing worldwide prevalence. We assessed… Expand

Stigmasterol inhibits lipopolysaccharide‐induced innate immune responses in murine models

Aaron Opoku Antwi, David Darko Obiri, Newman Osafo, Arnold Donkor Forkuo, Leslie B Essel

Biology, Medicine

International immunopharmacology

2017 (First Publication: 1 December 2017)

Abstract Stigmasterol is a naturally occurring steroid alcohol which occurs in vegetables, soya and a large variety of medicinal plants. Stigmasterol and other phytosterols have been documented as… Expand

Margaritaria discoidea (Euphorbiaceae) stem bark extract attenuates allergy and Freund's adjuvant-induced arthritis in rodents

David Darko Obiri, Newman Osafo, Joshua Oppong-Sarfo, Jude Prah

Medicine

Pharmacognosy research

2014 (First Publication: 1 April 2014)

Background: Various parts of Margaritaria discoidea find use in traditional medicine in the treatment of pain and oedema. This study evaluated the anti-allergic, anti-inflammatory and anti-arthritic… Expand

Anti-Inflammatory and Analgesic Activities of African Medicinal Plants

Christian Agyare, David Darko Obiri, Yaw Duah Boakye, Newman Osafo

Medicine

2013

Over a long period of time, several medicinal plants have been used for the treatment and management of various forms of inflammatory conditions by African traditional healers and herbalists. But… Expand

Antimicrobial Agents: Antibacterial Agents, Anti-biofilm Agents, Antibacterial Natural Compounds, and Antibacterial Chemicals

Yaw Duah Boakye, Newman Osafo, Cynthia Amaning Danquah, Francis Adu, Christian Agyare

Chemistry

2019 (First Publication: 13 February 2019)

The surge in antimicrobial resistance coupled with the decline in the antimicrobial drug pipeline calls for the discovery and development of new agents to tackle antibiotic resistance and prevent a… Expand

Antiallergic and Antiarthritic Effects of Stem Bark Extract of Glyphaea brevis (Spreng) Monachino (Tiliaceae) in Murine Models

David Darko Obiri, Newman Osafo, Regina Esinam Abotsi

Medicine

ISRN pharmacology

2013 (First Publication: 17 September 2013)

Background. Various parts of Glyphaea brevis (Spreng) Monachino (Tiliaceae) find a use in traditional medicine in the treatment of pain and oedema among others. This study evaluates the… Expand

Aqueous Ethanol Fruit Extract of Xylopia aethiopica and Xylopic Acid Exhibit Anti-Inflammatory Activity through Inhibition of the Arachidonic Acid Pathway

Newman Osafo, R. Biney, D. Obiri

Chemistry

2016 (First Publication: 1 December 2016)

In the form of a decoction, X. aethiopica is traditionally employed in the treatment of bronchitis, asthma, arthritis and rheumatism in Ghana, Nigeria and Cameroon. This study establishes the… Expand