Nevio Tosoratti

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We present a new coaxial antenna for microwave interstitial coagulative therapy, working at 2450 MHz and endowed with a miniaturized sleeve choke in order to reduce back heating effects and make the system response less dependent on the antenna insertion depth into the tissue; the way the choke is implemented makes the overall transversal size minimum and(More)
A new coaxial antenna for microwave ablation therapies is proposed. The antenna design includes a miniaturized choke and an arrowhead cap to facilitate antenna insertion into the tissues. Antenna matching and the shape and dimension of the area of ablated tissue (thermal lesion) obtained in ex vivo conditions are evaluated both numerically and(More)
PURPOSE The aim of this study was to characterise changes in tissue volume during image-guided microwave ablation in order to arrive at a more precise determination of the true ablation zone. MATERIALS AND METHODS The effect of power (20-80 W) and time (1-10 min) on microwave-induced tissue contraction was experimentally evaluated in various-sized cubes(More)
AIMS To compare the killing efficacy and the effects exerted by microwaves and conventional heating on structural and molecular components of Bacillus subtilis spores. METHODS AND RESULTS A microwave waveguide applicator was developed to generate a uniform and measurable distribution of the microwave electric-field amplitude. The applicator enabled the(More)
Although surgical resection is still the optimal treatment option for early-stage hepatocellular carcinoma (HCC) in patients with well compensated cirrhosis, thermal ablation techniques provide a valid non-surgical treatment alternative, thanks to their minimal invasiveness, excellent tolerability and safety profile, proven efficacy in local disease(More)
PURPOSE The aim of this study was to numerically and experimentally characterise the influence of tissues dimensions on the size and shape of microwave-induced ablation zones. MATERIALS AND METHODS A 2.45 GHz interstitial antenna was introduced into ex vivo bovine liver samples, delivering 60 W for 10 min; then the dimensions of the coagulated area were(More)
PURPOSE To evaluate the tolerability and safety of a newly designed probe for trans-perineal microwave thermoablation (TPMT) of the prostate in patients with benign prostatic hyperplasia (BPH), and the in vivo microwave effects on prostatic tissue. PATIENTS AND METHODS Nine patients with obstructive BPH who were candidates for open prostatectomy were(More)
OBJECTIVE To test the in vivo effects (toxicity, completeness of necrosis, dimensions of the lesion) of microwave thermoablation on porcine kidneys, using the Amica Probe v3 (Hospital Service SpA, Aprilia, Italy), in a refrigerated 17-G microwave applicator, that can be used to induce a spherical necrotic area. PATIENTS AND METHODS Six pigs were used;(More)
PURPOSE The aim of this study was to develop a predictive model of the shrinkage of liver tissues in microwave ablation. METHODS Thirty-seven cuboid specimens of ex vivo bovine liver of size ranging from 2 cm to 8 cm were heated exploiting different techniques: 1) using a microwave oven (2.45 GHz) operated at 420 W, 500 W and 700 W for 8 to 20 min,(More)
PURPOSE The aim of this study was to compare the performance of a microwave ablation (MWA) apparatus in preclinical and clinical settings. MATERIALS AND METHOD The same commercial 2.45 GHz MWA apparatus was used throughout this study. In total 108 ablations at powers ranging from 20 to 130 W and lasting from 3 to 30 min were obtained on ex vivo bovine(More)
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