Interdependence of integrative processes in the relays of the analyzers of signal stimuli (auditory and visual) was estimated by EP parameters (latency, amplitude, and duration) of the first positive and negative components. It has been shown that the significance of the coefficients of correlation between EP parameters in the studied structures is… (More)
4 Growing capacity of bioinformatic databases provides new opportunities to study structure-function relationship in large protein superfamilies and greatly increases the demand for high performance computing. However, the general-purpose parallel computing clusters do not provide optimal accommodation to bioinformatic applications which are usually written… (More)
Using microchemical methods for detection of dopamine (DA), noradrenaline (NA), serotonin (S) and its metabolite--5'-hydroxyindolilacetic acid (5'-HIAA) as well as the activity of neuromediator-utilising enzymes--MAO A and B and enzymes of acetylcholine metabolism--cholinacetyltranspherase (ChAT) and acetylcholinesterase (AChE), we revealed that synthetic… (More)
The article is devoted to commemoration of full member of Russian Academy of Medical Sciences, Oleg Andreevich Adrianov, who would have celebrated his 75-th anniversary in 1998. O. S. Adrianov, author of numerous works on physiology and morphology of central nervous system, in the recent years of his was studying the problem of the processes relationship at… (More)
Following amphetamine administration, the DSIP aggravated behavioural patterns but the EEG remained unaltered in the visual and motor cortex, and in the caudate nucleus. The findings suggest that the peptides modulating action depends on the way of dopamine hyperfunction initiation.
The resulting data give evidences, that after injection of the low doses of amphetamine the decrease of amplitudes both negative (NC-3), and positive components (PC-3) of the thalamo-cortical responses (TCR) of the sensorimotor cortex (SMC) takes place in 2nd-3d-weeks-old rabbits of their postnatal life. At the same time the amplitudes of these phases in… (More)
The complex neurophysiological, biochemical, and histochemical investigation carried out in dogs, cats, rabbits, and rats revealed the effects of taftsin (300 mcg/kg) at the macro- and microlevels within different periods (30 and 75 min) after its intraperitoneal injection. It was shown that after taftsin administration the configuration of evoked… (More)