Neuza S Domingues

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The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma

Antônio C Carvalho, Carlos E P Cunha, +31 authors Fernando Rodrigues
Genes and Immunity
2012

Non-Hodgkin lymphoma (NHL) has been associated with immunological defects, chronic inflammatory and autoimmune conditions. Given the link between immune dysfunction and NHL, genetic variants in… (More)

Mitochondrial dysfunction is the focus of quaternary ammonium surfactant toxicity to mammalian epithelial cells.

Ângela S. Inácio, Gabriel Nascimento Costa, +4 authors Otília V Vieira
Antimicrobial agents and chemotherapy
2013

Surfactants have long been known to have microbicidal action and have been extensively used as antiseptics and disinfectants for a variety of general hygiene and clinical purposes. Among surfactants,… (More)

In vitro effects of bis(1,2-dimethyl-3-hydroxy-4-pyridinonato)oxidovanadium(IV), or VO(dmpp)2, on insulin secretion in pancreatic islets of type 2 diabetic Goto-Kakizaki rats.

Julien Pelletier, Neuza S Domingues, Marcia C. Castro, Claes Göran Östenson
Journal of inorganic biochemistry
2016

Vanadium compounds have been explored as therapy of diabetes, and most studies have focussed on insulin mimetic effects, i.e. reducing hyperglycemia by improving glucose sensitivity and thus glucose… (More)

Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats.

Neuza S Domingues, J Pelletier, C Ostenson, Marcia C. Castro
Journal of inorganic biochemistry
2014

The bis(1,2-dimethyl-3-hydroxy-4-pyridinonato)oxidovanadium(IV), VO(dmpp)2, has shown anti-diabetic effects by in vitro studies in Wistar (W) rat adipocytes and in vivo in obese Zucker rats. The aim… (More)

Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis.

Ângela S. Inácio, Neuza S Domingues, +9 authors Otília V Vieira
The Journal of antimicrobial chemotherapy
2016

OBJECTIVES Broad-spectrum antimicrobial activity of quaternary ammonium surfactants (QAS) makes them attractive and cheap topical prophylactic options for sexually transmitted infections and… (More)

Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis

Inês B Santarino, Michelle S. Viegas, Neuza S Domingues, Ana M. Ribeiro, Miguel P Soares, Otília V Vieira
Scientific Reports
2017

Erythrophagocytosis, the phagocytic removal of damaged red blood cells (RBC), and subsequent phagolysosome biogenesis are important processes in iron/heme metabolism and homeostasis. Phagolysosome… (More)

Anaplasma marginale and Theileria annulata in questing ticks from Portugal

Sandra Antunes, Joana Ferrolho, Neuza S Domingues, Ana Sofia Santos, Maria Margarida Santos-Silva, Ana Domingos
Experimental and Applied Acarology
2016

Ticks are ubiquitous arthropods and vectors of several pathogenic agents in animals and humans. Monitoring questing ticks is of great importance to ascertain the occurrence of pathogens and the… (More)

Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages.

Neuza S Domingues, Luís M. B. B. Estronca, +10 authors Otília V Vieira
Biochimica et biophysica acta
2017

RATIONALE Cholesteryl hemiesters are oxidation products of polyunsaturated fatty acid esters of cholesterol. Their oxo-ester precursors have been identified as important components of the "core… (More)

Strategic bids in liberalized markets

Neuza S Domingues, Vitor Mendes
2008 5th International Conference on the European…
2008

This paper presents results of a study concerning the generation strategic bids for a single hour. In this study we incorporated the price and quantity bids. We considered an elastic demand curve,… (More)

Global Mixing Indices for Single Screw Extrusion

Neuza S Domingues, Americo Cunha, J. A. Covas

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