Chromoblastomycosis is a subcutaneous mycosis that remains a therapeutic challenge, with no standard treatment and high rates of relapse. On the basis of our recent discoveries in mouse models, we tested the efficacy of topical applications of imiquimod to treat patients afflicted with this chronic fungal infection. We report results of treatment for the… (More)
BACKGROUND Scarring alopecias are classified into primary and secondary types according to the initial site of inflammation. In primary scarring alopecias, the hair follicle is the main target of destruction; the term secondary cicatricial alopecia implies that follicular destruction is not the primary pathologic event. AIMS To review the histopathologic… (More)
Sycosiform tinea barbae caused by trichophyton rubrum and its association with autoinoculation Tinea barbae is a dermatophyte infection that affects primarily the bearded areas of the face.1 Sycosis is one type of clinical manifestation associated with deep folliculitis. The infection is usually caused by zoophilic fungi acquired after contact with animals… (More)
Neurothekeomas are rare benign dermal tumors, which originate from the peripheral nerve sheath. They are divided into myxoid, intermediate, and cellular types, based on the amount of myxoid matrix and on the immunohistochemical study. We report an unusual S-100 negative case of myxoid neurothekeoma, which is currently described in the literature as a new… (More)
Porokeratosis represents a group of disorders of epidermal keratinization that are characterized by one or more annular BLOCKINplaques BLOCKINsurrounded BLOCKINby BLOCKINa BLOCKINhistologically BLOCKINdistinctive BLOCKINhyperkeratotic BLOCKINridge-like BLOCKINborder BLOCKINcalled BLOCKINthe BLOCKINcornoid BLOCKINlamella.
Tyrosine BLOCKINkinase BLOCKINinhibitors BLOCKINare BLOCKINeffective BLOCKINas BLOCKINa BLOCKINtarget BLOCKINtherapy BLOCKINfor BLOCKINmalignant BLOCKINneoplasms.
BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. … (More)
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