Nestor L. Müller

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It is not known if a surgical lung biopsy is necessary in all patients for the diagnosis of idiopathic pulmonary fibrosis (IPF). We conducted a blinded, prospective study at eight referring centers. Initially, cases were evaluated by clinical history and examination, transbronchial biopsy, and high-resolution lung computed tomography scans. Pulmonologists(More)
OBJECTIVE We wanted to determine minimal tube current (mAs) required for consistently good image quality on conventional 10-mm collimation chest CT and effect of tube current reduction on detection of mediastinal and lung abnormalities. Tube current reduction is desirable to reduce patient radiation dose. SUBJECTS AND METHODS Prospectively, 30 consecutive(More)
OBJECTIVE We wanted to demonstrate and compare the serial high-resolution CTs (HRCT) and the pulmonary function test (PFT) findings of the usual interstitial pneumonia (UIP) and the non-specific interstitial pneumonia (NSIP). MATERIALS AND METHODS The serial HRCT scans and the PFT results were retrospectively analysed and compared for 35 patients having(More)
Symptoms of drug-associated interstitial lung disease (ILD) are nonspecific and can be difficult to distinguish from a number of illnesses that commonly occur in patients with non-small-cell lung cancer (NSCLC) on therapy. Identification of drug involvement and differentiation from other illnesses is problematic, although radiological manifestations and(More)
OBJECTIVE The objective of this study was to determine whether the various chronic cystic lung diseases can be differentiated on the basis of the pattern and distribution of abnormalities on high-resolution CT. MATERIALS AND METHODS High-resolution CT scans in 92 patients with chronic cystic lung diseases (18 with pulmonary Langerhans cell histiocytosis,(More)
The high-spatial-frequency (bone) reconstruction algorithm has been shown to be superior to the standard algorithm in the assessment of thin-section images of the lung parenchyma. We compared the high-spatial-frequency and standard algorithms in the evaluation of normal and abnormal lung parenchyma and mediastinum on conventional 10-mm-collimation CT scans.(More)
In recent years there have been major advances in chest imaging. These include significant refinements in previously available techniques such as computed tomography (CT) and magnetic resonance (MR) imaging and the introduction of new techniques into the clinical armamentarium, particularly positron emission tomography (PET) imaging. These advances have led(More)
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