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AIM The aim of the present study was to investigate the differences in the antioxidant-oxidant balance (AO-OB) between schizophrenic patients and healthy individuals and to explore the relationship of AO-OB with illness subtypes and symptom profiles. METHODS After a 15-day drug-free period, schizophrenia patients (n = 50) in a clinical sample, and age-(More)
OBJECTIVES We tested the hypothesis that metabolic disturbances in people with schizophrenia exist as a part of the schizophrenic syndrome, even when the antipsychotic drug effect is eliminated. We aimed to determine the prevalence of metabolic syndrome among patients with schizophrenia who were antipsychotic drug-naive or drug-free and their siblings for(More)
Heroin is among the most widely used and dangerous addictive opiate. The World Health Organization (WHO) estimated that more than 15 million people are under the influence of opiate addiction. The aim of this study was to investigate copper zinc-superoxide dismutase (Cu,Zn-SOD), catalase (CAT) and selenium-dependent glutathione peroxidase (Se-GPx)(More)
OBJECTIVE This study explores relevant outcomes with flexibly dosed paliperidone extended-release (ER) in a real-world design. RESEARCH DESIGN AND METHODS Patients were recruited from 23 countries. Adults with non-acute schizophrenia (n = 1812), previously unsuccessfully treated with other oral antipsychotics, were transitioned to paliperidone ER and(More)
OBJECTIVE To determine the level of insight among patients with schizophrenia and to compare sociodemographic and clinical features. METHOD The study included 66 patients with schizophrenia based on DSM-IV criteria. A semi-structured sociodemographic instrument, the Positive and Negative Syndrome Scale (PANSS), and the Schedule for Assessing the Three(More)
OBJECTIVE To determine cognitive and emotional changes among neurobrucellosis patients. METHODS The patients with neurobrucellosis and controls with brucellosis without neurologic involvement were included in the study. Neurobrucellosis was diagnosed by the following criteria: (i) symptoms or clinical findings compatible with neurobrucellosis, including(More)
Individuals with psychosocial problems such as social phobia or feelings of loneliness might be vulnerable to excessive use of cyber-technological devices, such as smartphones. We aimed to determine the relationship of smartphone addiction with social phobia and loneliness in a sample of university students in Istanbul, Turkey. Three hundred and sixty-seven(More)
Amaç: Alkolün beyinde yol açtığı nörodejenerasyona koruyucu yanıt olarak ortaya çıkan bir takım değişikliklerin, bağımlılık patogenezinde rol aldığı bilinmektedir. Kronik alkol alımının yol açtığı nörotoksik mekanizmalar tam olarak aydınlatılmış olmasa da, güncel çalışmalarda uzamış alkol alımının, öğrenme ve hafıza gibi bilişsel işlevlerde rol alan protein(More)
Illicit drugs are often used as aphrodisiacs to enhance sexual performance and/or pleasure; however, the available data suggest that most illicit drugs have adverse effects on erection, sexual desire and ejaculation latency in males and that these effects are not fully understood. This study aimed to determine the effect of illicit drug abuse on male sexual(More)